What is L-PRF?
L-PRF is a concentrated platelet content extracted from your own blood, which has been used in the field of wound and regenerative medicine for a very long time.
L-PRF stands for Leucocyte Platelet Rich Fibrin, which is comprised of white cells, platelets, growth factors, and an organised fibrin network. This novel biotechnology employs your own blood (autologous) and a concentrated form of platelets (APC). This biomedical procedure was created some years ago and has been developed to promote tissue healing.
The Clinical Challenge
Following tooth loss caused by caries, root infection, periodontal disease or restorative failures, the supporting bone undergoes severe resorption. Reduced volume and quality of the residual alveolar ridge offer clinical challenges for both oral surgeons and dentists to replace the missing tooth by means of dental implants in the most appropriate position. On the other hand, the presence of remaining tissue defect around the implants results in aesthetic disturbances and food accumulation, as well as poor implant-bone support.
How is L-PRF Prepared?
The same procedure is undertaken as if you were having a routine blood test. Typically, 2 to 6 tubes of 9 mL blood are taken from you by your specialist dentist and inserted into a Swiss-made centrifuge to separate and concentrate active proteins and certain important blood cells.
Using this dedicated centrifuge, certain regenerative cells and tissue growth factors are concentrated in a blood tube. This is an ideal auxiliary healing means, extracting your own body’s healing proteins, growth factors, and cells within a meshwork of fibres to access your own healing based on the indication of use.
The L-PRF is prepared in different customisations such as L-PRF membrane, L-PRF clot, and L-PRF liquid, which are super rich in comparison to normal blood. Dentists at London Specialist Dentists combine L-PRF with different graft replacement materials to restore hard tissue defects caused by significant bone loss in different regenerative surgical procedures.
What Types of Treatments Apply L-PRF?
London Specialist Dentists use L-PRF in most holistic regenerative surgeries, including dental and oral maxillofacial procedures such as:
- Dental implants
- Extraction sockets
- Sinus augmentation
L-PRF has also been used successfully in other medical fields such as orthopaedics, dermatology, and hair transplant.
YOUR OWN POWER TO HEAL
What is Platelet Fibrin Therapy?
L-PRF, in its plural forms of clots, membranes, and liquid, promotes healing.
After the application of the blood clot, a series of bioactive growth factors and cells are released into the tissue defect after the regenerative surgery is undertaken, which gradually enhances tissue healing.
Key characteristics of L-PRF therapy:
- 100% natural
- Applies no additives, chemicals, or foreign substances—purely your own concentrated blood
- Employs the latest technology and is both FDA and EC approved
- Provides enhanced healing using your own blood with anti-inflammatory and antibacterial properties
- Reduces significantly the postoperative pain and discomfort, hence recovery time
- Requires only a small blood sample
- Virtually painless
- Biocompatible
- Lowered risk for complications
- Promotes efficient healing and recovery
Is the Procedure Painful?
No, it is a painless procedure—as routine and simple as a normal blood test draw.
BETTER HELAING FROM WITHIN
How Does L-PRF Work to Heal?
As mentioned, the concentrated L-PRF contains proteins, white blood cells (leukocytes), growth factors, and a scaffold of meshwork of fibres. These elements release growth factors during the course of healing to promote more efficient healing via communication with other cells and tissues.
L-PRF has a longer lifespan and releases growth factors at the local site after 14 days, compared to standard platelet-rich plasma (PRP), which releases growth factors after only 3 or 4 days. This extended release period means sustained regenerative support throughout the critical early stages of healing.
A NATURAL CHOICE PURE & SIMLE
Are There Any Side Effects or Complications from L-PRF?
This is the most frequently asked question. L-PRF contains no foreign elements, foreign bodies, chemicals, or non-tissue field products. It is purely concentrated platelets from your own body.
The treatment is additive-free and 100% natural, requiring no artificial chemical compounds with no risk of contagious micro-organisms transferred by other humans or animals. Therefore, there would be no allergies or side effects following the application of L-PRF. As a result, your own body will produce proteins and other bioactive agents as well as fibrin scaffolds to accelerate and optimise the healing process.
L-PRF neither causes any allergic reaction, foreign body reaction, or other side effect when introduced to your pulp, extraction socket, implant placement area, or other region which requires dental alveolar healing and regeneration.
Technology Innovation
London Specialist Dentists use the latest technology and innovations in all fields of dentistry. The Intra-Spin™ System provides a biologically predictable centrifuging protocol that does not contain any synthetic, animal, or human traces. The produced L-PRF is preserved by a strong fibrin-matrix mesh, improving its biological and handling properties. This purest form of L-PRF can be directly placed into the tissue defect or combined with other biomaterials (L-PRF Block™) to promote the healing process.
Summary
L-PRF represents a natural, biologically predictable approach to tissue regeneration using your own body’s healing capacity. With no foreign substances, no allergic reactions, and proven efficacy in dental and medical applications, L-PRF therapy offers patients a safe, effective means of optimising healing outcomes in regenerative surgical procedures.